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As a dye intermediate, 5-Amino-O-Cresol plays a key role in which specific dye synthesis processes?

Publish Time: 2025-02-06
As a dye intermediate, 5-Amino-O-Cresol plays a key role in a variety of specific dye synthesis processes.

Synthesis of o-methyl salicylic acid:

5-Amino-O-Cresol can be made into 5-Amino-O-Cresol sodium by carboxylation reaction through Kolbe-Schmitt method.

5-Amino-O-Cresol sodium is then carboxylated with CO2 under certain pressure conditions, and then acidified to obtain the product o-methyl salicylic acid.

o-Methyl salicylic acid is mainly used to make azo dyes, especially acid mordant blue B dyes. It can be used as a raw material to prepare more than 20 triphenylmethane mordant dyes such as blue, purple, brown and green.

Herbicides in synthetic pesticides:

5-Amino-O-Cresol is chlorinated to generate 4-chloro-5-Amino-O-Cresol, which is the main raw material for chlorophenoxyacetic acid herbicides.

For example, herbicides 2-methyl-4-chloro (2-methyl-4-chlorophenoxyacetic acid MCPA), 2-methyl-4-chloropropionic acid [2-(2-methyl-4-chlorophenoxy) propionic acid MCPP], 2-methyl-4-chlorobutyric acid [2-(2-methyl-4-chlorophenoxy) butyric acid MCPB], etc. can be synthesized.

Synthesis of other dye intermediates:

5-Amino-O-Cresol can be nitrated to obtain 4,6-dinitro-5-Amino-O-Cresol (DNOC), which has both herbicidal and insecticidal effects.

5-Amino-O-Cresol is alkylated with propylene to generate 2-methyl-5-isopropylphenol, which can be used as a preservative and fragrance.

5-Amino-O-Cresol can also be used as a raw material to synthesize other dye intermediates, further enriching the types and application areas of dye products.

In summary, 5-Amino-O-Cresol has a wide range of application value in the field of dye synthesis and is a key raw material in the synthesis of various dyes and pesticides. Its unique chemical properties and reactivity make it occupy an important position in the dye industry.
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